{"id":610948,"date":"2024-06-11T04:02:30","date_gmt":"2024-06-11T08:02:30","guid":{"rendered":"https:\/\/platohealth.ai\/mostly-discouraging-trial-of-msc-nps-or-purported-neural-cells-from-mscs-for-ms-the-niche-2\/"},"modified":"2024-06-11T04:26:16","modified_gmt":"2024-06-11T08:26:16","slug":"mostly-discouraging-trial-of-msc-nps-or-purported-neural-cells-from-mscs-for-ms-the-niche-2","status":"publish","type":"post","link":"https:\/\/platohealth.ai\/mostly-discouraging-trial-of-msc-nps-or-purported-neural-cells-from-mscs-for-ms-the-niche-2\/","title":{"rendered":"Mostly discouraging trial of MSC-NPs or purported neural cells from MSCs for MS – The Niche","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"
The idea of mesenchymal cells or MSCs for MS has been around for a long time. However, there haven\u2019t been that many strong clinical trials testing it. There\u2019s a new paper out that reports one of the stronger MSC-related trials for MS in terms of design. In this case, they didn\u2019t use just MSCs but reported deriving a \u201cneural progenitor\u201d population from the MSCs. They call these cells MSC-NPs.<\/p>\n
How\u2019d it turn out?<\/p>\n
The main takeaway is that this is a discouraging trial but they say that some patients may have benefited. Overall, there are some interesting elements to this including the idea of MSC-NPs.<\/p>\n Let\u2019s do a quick journal club-type review of this paper.<\/p>\nJournal club review of MSCs for MS trial paper: overview<\/h2>\n