{"id":600530,"date":"2024-05-28T15:04:29","date_gmt":"2024-05-28T19:04:29","guid":{"rendered":"https:\/\/platohealth.ai\/mental-health-awareness-month-how-cirm-is-advancing-research-for-neuropsychiatric-disorders\/"},"modified":"2024-05-28T16:55:37","modified_gmt":"2024-05-28T20:55:37","slug":"mental-health-awareness-month-how-cirm-is-advancing-research-for-neuropsychiatric-disorders","status":"publish","type":"post","link":"https:\/\/platohealth.ai\/mental-health-awareness-month-how-cirm-is-advancing-research-for-neuropsychiatric-disorders\/","title":{"rendered":"Mental Health Awareness Month: How CIRM is advancing research for neuropsychiatric disorders","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"
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Since 1949, Mental Health Awareness Month has been observed in May each year to increase awareness of the importance of mental health and wellness in America.  <\/p>\n

In California, it is estimated<\/a> that 1.2 million adults have a serious mental illness and that 5.6 million adults have a mental health condition. <\/p>\n

Today, neuropsychiatric disorders continue to exert a tremendous burden on patients and caretakers across California and the nation, and effective treatments for these diseases remain a significant unmet medical need.  <\/p>\n

The California Institute for Regenerative Medicine (CIRM) is proud to support innovative research and the development of novel therapeutics to address this pressing need.<\/p>\n

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CIRM\u2019s commitment to central nervous system (CNS) disease research<\/h2>\n

Approved by California voters in 2020, Proposition 14 dedicates at least $1.5 billion of CIRM\u2019s $5.5 billion total bond funding to the support of research and development of treatments for diseases and conditions of the brain and central nervous system, building on CIRM\u2019s long-standing support for neuroscience research from foundational discoveries to clinical trials. <\/p>\n

CIRM\u2019s ReMIND program<\/strong> <\/h2>\n

To accelerate scientific understanding of neuropsychiatric disease, CIRM launched a new multidisciplinary funding program in 2023 called ReMIND (Research using Multidisciplinary Innovative approaches in Neuro Diseases).<\/a>  <\/p>\n

ReMIND supports discovery-stage research that leverages collaborative efforts across California and was developed in part to build on the exciting advances in stem cells and genetic research in this field. <\/p>\n

\u201cEffective treatments for neuropsychiatric diseases remain a significant unmet medical need in California, the US and the World. The ReMIND program is part of a deliberate drive at CIRM to support multidisciplinary discovery research as a way to catalyze innovation, especially in areas of large potential impact,\u201d said Dr. Rosa Canet-Aviles, VP of Scientific Programs and Education at CIRM. <\/p>\n

ReMIND-L (DISC 4)<\/h2>\n

In May 2024, CIRM received 26 applications for its first funding opportunity\u2014ReMIND-L (DISC4)\u2014from 11 academic institutions across the state. A majority of the applications involved cross-institutional collaborations.  <\/p>\n

In total, over 150 California investigators (including 40% women investigators) participated as core members in these applications. The proposed research spans multiple neuropsychiatric disorders, including schizophrenia, major depression, substance use disorders, as well as autism.<\/p>\n

Upcoming funding opportunities: ReMIND-X (DISC 5)<\/h2>\n

Building on this effort, a second collaborative funding opportunity under the ReMIND umbrella, ReMIND-X, will support exploratory studies led by collaborative teams of 2-3 investigators to test novel models, tools, technologies, and hypotheses.  <\/p>\n

Funding decisions for ReMIND-L (DISC4) are expected later this year. <\/p>\n

The Request for Applications (RFA) for ReMIND-X will be available in late 2024\/early 2025. Interested applicants are encouraged to visit the ReMIND webpage<\/a> for more information. <\/p>\n

Together, CIRM\u2019s ReMIND research programs have the potential to impact Californians and the world to find new disease mechanisms for mental health disorders. <\/p>\n