{"id":489780,"date":"2024-01-19T06:56:11","date_gmt":"2024-01-19T11:56:11","guid":{"rendered":"https:\/\/platohealth.ai\/can-prp-help-rheumatoid-arthritis-patients-regenexx\/"},"modified":"2024-01-19T07:56:01","modified_gmt":"2024-01-19T12:56:01","slug":"can-prp-help-rheumatoid-arthritis-patients-regenexx","status":"publish","type":"post","link":"https:\/\/platohealth.ai\/can-prp-help-rheumatoid-arthritis-patients-regenexx\/","title":{"rendered":"Can PRP Help Rheumatoid Arthritis Patients? – Regenexx","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

Home<\/a> \u203a Blog<\/a> \u203a Can PRP Help Rheumatoid Arthritis Patients?<\/span><\/span><\/span><\/span><\/p>\n

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I have been very cautious in recommending orthobiologics to patients with rheumatoid arthritis (RA). However, recently I found high-quality data on using PRP in these patients. So what does that say? Does PRP help patients with RA?<\/p>\n

What is RA and How is It Different than OA?<\/h2>\n

Rheumatoid arthritis (RA) is an inflammatory disease where the immune system attacks the joints. Osteoarthritis (OA) is caused by many factors, but the key thread connecting them all is wear and tear. RA is also different in that it used to lead to very severe disabling disease that could be life-threatening if the disease attacked the upper neck. Now that disease-modifying drugs are available, severe RA cases can be controlled.<\/p>\n

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Why Was I Cautious About Recommending Orthobiologics in RA Patients?<\/h2>\n

RA patients often take powerful anti-inflammatory biologic drugs to reduce the joint destruction that happens due to this disease. The concern was that these drugs would interefere with the normal inflammatory process believed to be a part of how PRP works.<\/p>\n

A Surprising PRP Study I Hadn\u2019t Indexed<\/h2>\n

When I publish my PRP infographics and study reviews on PRP I tend to search the US Library of Medicine under PRP and various conditions like knee osteoarthritis or shoulder rotator cuff tear. That works well for getting studies about common issues identified. However, it also caused me to miss an important randomized controlled trial on RA and PRP.<\/p>\n

A patient had asked a clinic staff member about whether there was research showing that PRP helped RA. I then quickly search PubMed for \u201cPRP Rheumatoid Arthritis Randomized\u201d and this new study popped up.<\/p>\n

In this 2021 Randomized Controlled Trial, researchers took 60 rheumatoid arthritis patients who met ACR-EULAR criteria with low disease activity who were being treated with non-biologic DMARDs for 3 months. These patients had the following joints involved and injected:<\/p>\n