ARTICLE | Discovery & Translation
BioCentury’s roundup of translational innovations
By Danielle Golovin, Senior Biopharma Analyst
April 27, 2024 12:03 AM UTC
Serial entrepreneur Lieping Chen led a study in Science Immunology that identified a phospholipase that reduces response to immunotherapy by blocking T cell infiltration into tumors.
Authors from NextCure Inc. (NASDAQ:NXTC), Normunity Inc. and Yale University performed a genome-wide screen of over 1,000 soluble human proteins enriched in the tumor microenvironment and identified PLA2G10 as a T cell excluder that is highly expressed in several cancers…
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- Source: https://www.biocentury.com/article/652255/science-spotlight-tumor-t-cell-restriction-mechanism-plus-programmable-rna-excision