ARTICLE | Discovery & Translation
BioCentury’s roundup of translational innovations
By Danielle Golovin, Senior Biopharma Analyst
June 13, 2024 12:07 AM UTC
A subcutaneously injected biodegradable scaffold containing T cell-activating ligands could boost the antitumor efficacy of previously administered CAR T cells.
A team from Harvard University and collaborators at the Dana-Farber Cancer Institute showed that injecting a lymphoma mouse model with a biodegradable scaffold, after administration of CD19-targeted CAR T cells, increased local activation and infiltration of cytotoxic T cells, CAR T cell expansion, antitumor immunity and overall survival compared with the CAR T cells alone. …
- SEO Powered Content & PR Distribution. Get Amplified Today.
- PlatoData.Network Vertical Generative Ai. Empower Yourself. Access Here.
- PlatoAiStream. Web3 Intelligence. Knowledge Amplified. Access Here.
- PlatoESG. Carbon, CleanTech, Energy, Environment, Solar, Waste Management. Access Here.
- PlatoHealth. Biotech and Clinical Trials Intelligence. Access Here.
- Source: https://www.biocentury.com/article/652653/science-spotlight-lyell-s-scaffold-for-reenergizing-car-t-cells-plus-cirrus-denali-and-more