
Malagola M, Rambaldi B, Ravizzola G, Cattaneo C, Borlenghi E, Polverelli N, et al. Bacterial blood stream infections negatively impact on outcome of patients treated with allogeneic stem cell transplantation: 6 years single-centre experience. Mediterr J Hematol Infect Dis. 2017;9:e2017036.
Gudiol C, Garcia-Vidal C, Arnan M, Sánchez-Ortega I, Patiño B, Duarte R, et al. Etiology, clinical features and outcomes of pre-engraftment and post-engraftment bloodstream infection in hematopoietic SCT recipients. Bone Marrow Transplant. 2014;49:824–30.
Weisser M, Theilacker C, Tschudin Sutter S, Babikir R, Bertz H, Götting T, et al. Secular trends of bloodstream infections during neutropenia in 15 181 haematopoietic stem cell transplants: 13-year results from a European multicentre surveillance study (ONKO-KISS). Clin Microbiol Infect. 2017;23:854–9.
Cao W, Guan L, Li X, Zhang R, Li L, Zhang S, et al. Clinical analysis of bloodstream infections during agranulocytosis after allogeneic hematopoietic stem cell transplantation. Infect Drug Resist. 2021;14:185–92.
Kikuchi M, Akahoshi Y, Nakano H, Ugai T, Wada H, Yamasaki R, et al. Risk factors for pre- and post-engraftment bloodstream infections after allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2015;17:56–65.
Gill J, Busca A, Cinatti N, Passera R, Dellacasa CM, Giaccone L, et al. Bacterial bloodstream infections after allogeneic hematopoietic stem cell transplantation: etiology, risk factors and outcome in a single-center study. Microorganisms. 2023;11:742.
Song W, Song X, Zhu Y, Ren Y, Xu J, Zhu Q. Microbiology and clinical outcome of bloodstream infections in patients after hematopoietic stem cell transplantation. Infect Drug Resist. 2023;16:5375–86.
Mikulska M, Raiola AM, Galaverna F, Balletto E, Borghesi ML, Varaldo R, et al. Pre-engraftment bloodstream infections after allogeneic hematopoietic cell transplantation: impact of T Cell-replete transplantation from a haploidentical donor. Biol Blood Marrow Transpl. 2018;24:109–18.
Wisplinghoff H, Seifert H, Wenzel RP, Edmond MB. Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in Hospitals in the United States. Clin Infect Dis. 2003;36:1103–10.
Ramphal R. Changes in the etiology of bacteremia in febrile neutropenic patients and the susceptibilities of the currently isolated pathogens. Clin Infect Dis. 2004;39:S25–31.
Averbuch D, Tridello G, Hoek J, Mikulska M, Akan H, Yaňez San Segundo L, et al. Antimicrobial resistance in gram-negative rods causing bacteremia in hematopoietic stem cell transplant recipients: intercontinental prospective study of the infectious diseases working party of the european bone marrow transplantation group. Clin Infect Dis. 2017;65:1819–28.
Cappellano P, Viscoli C, Bruzzi P, Van Lint MT, Alberto C, Pereira P. et al. Epidemiology and risk factors for bloodstream infections after allogeneic hematopoietic stem cell transplantion. New Microbiol. 2007;30:89–99.
Chumbita M, Puerta-Alcalde P, Gudiol C, Garcia-Pouton N, Laporte-Amargós J, Ladino A, et al. Impact of empirical antibiotic regimens on mortality in neutropenic patients with bloodstream infection presenting with septic shock. Antimicrob Agents Chemother. 2022;66:e0174421.
Puerta-Alcalde P, Chumbita M, Charry P, Castaño-Díez S, Cardozo C, Moreno-García E, et al. Risk factors for mortality in hematopoietic stem cell transplantation recipients with bloodstream infection: points to be addressed by future guidelines. Transpl Cell Ther. 2021;27:501.e1–501.e6.
Ji J, Klaus J, Burnham JP, Michelson A, McEvoy CA, Kollef MH, et al. Bloodstream infections and delayed antibiotic coverage are associated with negative hospital outcomes in hematopoietic stem cell transplant recipients. Chest. 2020;158:1385–96.
Carreira AS, Salas MQ, Remberger M, Basso IN, Law AD, Lam W, et al. Bloodstream infections and outcomes following allogeneic hematopoietic cell transplantation: a single-center study. Transpl Cell Ther. 2022;28:50.e1–50.e8.
Averbuch D, Orasch C, Cordonnier C, Livermore DM, Mikulska M, Viscoli C, et al. European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia. Haematologica. 2013;98:1826–35.
Puerta-Alcalde P, Cardozo C, Marco F, Suárez-Lledó M, Moreno E, Morata L, et al. Changing epidemiology of bloodstream infection in a 25-years hematopoietic stem cell transplant program: current challenges and pitfalls on empiric antibiotic treatment impacting outcomes. Bone Marrow Transpl. 2020;55:603–12.
Liu YF, Liu Y, Chen X, Jia Y. Epidemiology, drug resistance, and risk factors for mortality among hematopoietic stem cell transplantation recipients with hospital-acquired Klebsiella pneumoniae infections: a single-center retrospective study from China. Infect Drug Resist. 2022;15:5011–21.
Bacigalupo A, Ballen K, Rizzo D, Giralt S, Lazarus H, Ho V, et al. Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transplant. 2009;15:1628–33.
Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, et al. Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients. Bone Marrow Transpl. 2020;55:1114–25.
Gustinetti G, Mikulska M. Bloodstream infections in neutropenic cancer patients: a practical update. Virulence. 2016;7:280–97.
Mikulska M, Del Bono V, Raiola AM, Bruno B, Gualandi F, Occhini D, et al. Blood stream infections in allogeneic hematopoietic stem cell transplant recipients: reemergence of gram-negative rods and increasing antibiotic resistance. Biol Blood Marrow Transplant. 2009;15:47–53.
Sanz J, Cano I, González-Barberá EM, Arango M, Reyes J, Montesinos P, et al. Bloodstream infections in adult patients undergoing cord blood transplantation from unrelated donors after myeloablative conditioning regimen. Biol Blood Marrow Transplant. 2015;21:755–60.
Yan CH, Wang Y, Mo XD, Sun YQ, Wang FR, Fu HX, et al. Incidence, risk factors, microbiology and outcomes of pre-engraftment bloodstream infection after haploidentical hematopoietic stem cell transplantation and comparison with HLA-identical sibling transplantation. Clin Infect Dis. 2018;67:S162–73.
Oltolini C, Greco R, Galli L, Clerici D, Lorentino F, Xue E, et al. Infections after allogenic transplant with post-transplant cyclophosphamide: impact of donor HLA matching. Biol Blood Marrow Transplant. 2020;26:1179–88.
Young JAH, Logan BR, Wu J, Wingard JR, Weisdorf DJ, Mudrick C, et al. Infections after transplantation of bone marrow or peripheral blood stem cells from unrelated donors. Biol Blood Marrow Transplant. 2016;22:359–70.
Kara Ali R, Surme S, Balkan II, Salihoglu A, Sahin Ozdemir M, Ozdemir Y, et al. An eleven-year cohort of bloodstream infections in 552 febrile neutropenic patients: resistance profiles of Gram-negative bacteria as a predictor of mortality. Ann Hematol. 2020;99:1925–32.
Bock AM, Cao Q, Ferrieri P, Young JAH, Weisdorf DJ. Bacteremia in blood or marrow transplantation patients: clinical risk factors for infection and emerging antibiotic resistance. Biol Blood Marrow Transplant. 2013;19:102–8.
Mikulska M, Del Bono V, Prinapori R, Boni L, Raiola AM, Gualandi F, et al. Risk factors for enterococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients. Transpl Infect Dis. 2010;12:505–12.
Stoma I, Karpov I, Milanovich N, Uss A, Iskrov I. Risk factors for mortality in patients with bloodstream infections during the pre-engraftment period after hematopoietic stem cell transplantation. Blood Res. 2016;51:102–6.
Albasanz-Puig A, Gudiol C, Puerta-Alcalde P, Ayaz CM, Machado M, Herrera F, et al. Impact of the inclusion of an aminoglycoside to the initial empirical antibiotic therapy for gram-negative bloodstream infections in hematological neutropenic patients: a propensity-matched cohort study (AMINOLACTAM study). Antimicrob Agents Chemother. 2021;65:10–1128.
Teshome BF, Park T, Arackal J, Hampton N, Kollef MH, Micek ST. Preventing new gram-negative resistance through beta-lactam de-escalation in hospitalized patients with sepsis: a retrospective cohort study. Clin Infect Dis. 2024;6:ciae253
Kamboj M, Cohen N, Huang YT, Kerpelev M, Jakubowski A, Sepkowitz KA, et al. Impact of empiric treatment for vancomycin-resistant enterococcus in colonized patients early after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2019;25:594–8.
Papanicolaou GA, Ustun C, Young JAH, Chen M, Kim S, Woo Ahn K, et al. Bloodstream infection due to vancomycin-resistant enterococcus is associated with increased mortality after hematopoietic cell transplantation for acute leukemia and myelodysplastic syndrome: a multicenter, retrospective cohort study. Clin Infect Dis. 2019;69:1771–9.
Lafuente Cabrero E, Terradas Robledo R, Civit Cuñado A, García Sardelli D, Hidalgo López C, Giro Formatger D, et al. Risk factors of catheter- associated bloodstream infection: systematic review and meta-analysis. PLoS ONE. 2023;18:e0282290.
- SEO Powered Content & PR Distribution. Get Amplified Today.
- PlatoData.Network Vertical Generative Ai. Empower Yourself. Access Here.
- PlatoAiStream. Web3 Intelligence. Knowledge Amplified. Access Here.
- PlatoESG. Carbon, CleanTech, Energy, Environment, Solar, Waste Management. Access Here.
- PlatoHealth. Biotech and Clinical Trials Intelligence. Access Here.
- Source: https://www.nature.com/articles/s41409-024-02494-x