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The Adoption of Organ-on-Chips in Industry: A Status Report for 2024

Organ-on-chips, also known as microphysiological systems, are a cutting-edge technology that has been gaining traction in various industries in recent...

Autonomix Medical Inc. is making waves in the medical industry with its innovative nerve treatment technology, as highlighted in a...

In the pharmaceutical industry, ensuring compliance with regulations and guidelines is of utmost importance. One critical aspect of compliance is...

Sugar processing is a crucial step in the production of various sweeteners and food products. The efficiency of this process...

Studies Study First Submitted Date 2019-03-27 Study First Posted Date 2019-03-29 Last Update Posted Date 2023-04-19 Start Month Year April...

Sanofi, the pharmaceutical company behind the popular heartburn medication Zantac, has reached a resolution in the majority of lawsuits filed...

India has taken a significant step forward in the field of healthcare with the launch of its first home-grown gene...

The Brain & Behavior Research Foundation is a leading non-profit organization dedicated to funding cutting-edge research on mental health disorders....

Biotech Land is a leading company in the field of biotechnology, specializing in the development of innovative products derived from...

Biopharmaceutical companies are constantly seeking ways to improve the efficiency and effectiveness of their clinical trials. One emerging technology that...

In a groundbreaking development for the hemp industry, regulatory clearance has been granted for bioengineered hemp in the latest Bio.News...

Aardvark Therapeutics, a biotechnology company specializing in developing innovative treatments for rare diseases, is gearing up for a $200 million...

New research has shed light on the historic range of the elusive Canada lynx in the United States, suggesting that...

Studies Study First Submitted Date 2019-06-12 Study First Posted Date 2019-06-18 Last Update Posted Date 2023-07-06 Start Month Year April...

Studies Study First Submitted Date 2019-06-12 Study First Posted Date 2019-06-19 Last Update Posted Date 2023-07-06 Start Month Year April...

A groundbreaking study has recently shed light on a potential new approach to improving immune function by depleting the hematopoietic...

A recent study published in Nature Communications has revealed the potential of a new protein language model to enhance sequence...

Researchers have made significant advancements in the field of tissue engineering by creating grafts that closely mimic the structure and...

Scientists have made a groundbreaking advancement in the field of regenerative medicine by creating artificial ear grafts that closely mimic...

The Hevolution Foundation, a non-profit organization dedicated to supporting innovative solutions in healthcare, has recently announced a $115 million funding...

Hevolution Foundation, a non-profit organization dedicated to supporting innovative solutions in healthcare, is currently seeking applicants for $115 million in...

Boundless Bio, a biotechnology company focused on developing innovative cancer therapies, recently made headlines with its successful initial public offering...

Indoor air quality (IAQ) is a critical aspect of public health and safety, especially in public buildings where large numbers...

GLP-1, or glucagon-like peptide-1, is a hormone that plays a crucial role in regulating blood sugar levels in the body....

Synaptic proteins play a crucial role in the development and function of the nervous system. These proteins are responsible for...

In today’s fast-paced and competitive business environment, understanding the relationship between various factors to drive growth forces is essential for...

Lung fibrosis is a debilitating and often fatal condition characterized by scarring of the lung tissue, leading to difficulty breathing...

Rice University biologists have recently discovered a new species of tiger beetle, named Eunota houstoniana, in the Houston area. This...

Moderna, a leading biotechnology company known for its groundbreaking mRNA technology, has recently secured a significant investment from Blackstone for...

Zepbound is a prescription medication approved in 2023 by the U.S. Food and Drug Administration (FDA) for chronic weight management. ...

Towards A Gender-specific And Morphology-specific Assessment Of Aortic Valve Stenosis Severity – Renal.PlatoHealth.ai

Over the last two decades, the differentiation of severe from non-severe aortic valve stenosis with echocardiography has become more complex. The consideration of flow is now frequently essential to evaluate haemodynamic stenosis severity. Low flow can result in low gradient and, thereby, mask severe aortic stenosis. On the other hand, low flow may impede complete opening of the valve and result in overestimation of the severity by aortic valve area (AVA). Since echocardiographic assessment of flow incorporates parameters which are also used to quantify gradient and AVA, measurement errors may lead to major misclassifications of the disease. This has stimulated the search for a method evaluating stenosis severity by morphological criteria independent of haemodynamics. European Society of Cardiology/European Association for Cardio-Thoracic Surgery Guidelines for the management of valvular heart disease 2021 recommend quantification of valve calcification by CT for assessing the severity of aortic stenosis in patients with low gradient. Aortic valve calcification is measured in (arbitrary) Agatston units (AU), and the diagnosis of severe aortic stenosis considered likely with values >2000 in men and >1200 in women. In the two main studies in this field,1 2 areas under the curve (AUCs) from receiver operating characteristic (ROC) for the diagnosis of severe aortic stenosis compared with echocardiography were …