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How a Healthy Lifestyle Can Reduce Genetic Risk for Early Death by 62%

Living a healthy lifestyle can have a significant impact on reducing the risk of early death, even for individuals with...

Maintaining a healthy lifestyle is not only important for overall well-being, but new research suggests it may also play a...

The Food and Drug Administration (FDA) has recently approved an Investigational New Drug (IND) application for VYN202, a novel BD2-selective...

The Indian Pharmacopoeia Commission (IPC) and the Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTech) have recently announced...

A recent Phase 2 clinical trial of the lead NOX inhibitor candidate, setanaxib, has shown promising results in the treatment...

The Food and Drug Administration (FDA) has recently approved Myhibbin (mycophenolate mofetil) oral suspension for the prevention of organ rejection...

BioPharma Services, a leading contract research organization (CRO) specializing in early-phase clinical trials, has recently announced that they have received...

The Association of Clinical Research Professionals (ACRP) recently released its 2024 report, highlighting the challenges faced by the clinical research...

The Association of Clinical Research Professionals (ACRP) recently released a report titled “ACRP 2024: Workforce and Patient Engagement in Clinical...

A recent Phase 2 clinical trial has shown promising results for the use of Erleada in combination with androgen deprivation...

Endometriosis is a common yet often misunderstood condition that affects millions of women worldwide. It occurs when tissue similar to...

A recent study has revealed promising results that suggest blood pressure medication may not only help lower blood pressure, but...

Amolyt Pharma, a biopharmaceutical company focused on developing innovative treatments for rare endocrine and metabolic diseases, recently announced that the...

The Environmental Protection Agency (EPA) has recently announced a significant allocation of $3 billion for the nationwide replacement of lead...

A new vaccine has shown promising results in protecting against a drug-resistant superbug in mice, according to a recent study...

Clinical research professionals play a crucial role in the development of new treatments and therapies for cancer patients. As part...

A recent study published in the journal Obesity has found that when it comes to weight loss, the number of...

When conducting a research study, selecting appropriate endpoints is crucial in order to accurately measure the outcomes of the study....

A promising new development has emerged in the field of cancer treatment, specifically for patients with B-cell lymphoma. The Phase...

The clinical trials industry plays a crucial role in the development of new medical treatments and therapies. In recent years,...

Summer camp can be a fun and exciting experience for children, but for those with allergies and asthma, it can...

Clinical trials are a crucial component of the medical research process, helping to determine the safety and effectiveness of new...

HealthTech, or healthcare technology, has revolutionized the way clinical trials are conducted in the medical field. With the integration of...

In the world of healthcare and clinical research, the use of technology has become increasingly important in collecting and analyzing...

Small cell lung cancer (SCLC) is a highly aggressive form of lung cancer that accounts for approximately 15% of all...

Relyvrio, a controversial drug used to treat ALS (amyotrophic lateral sclerosis), is being pulled off the market by its maker,...

Pharmacovigilance is a crucial aspect of the healthcare industry that focuses on monitoring and assessing the safety of pharmaceutical products....

A groundbreaking Phase 2a clinical trial of regenerative cell therapy for end-stage liver disease has recently begun, with the first...

Wet age-related macular degeneration (AMD) is a chronic eye disease that can cause severe vision loss in older adults. It...

A new study published in Drugs.com MedNews has shown promising results for a transdermal microporation system using zolmitriptan in the...

New Standard-of-Care for MCL Possible with Combination Treatment

Mantle cell lymphoma (MCL) is a rare and aggressive form of non-Hodgkin lymphoma that typically affects older adults. While advancements in treatment have improved outcomes for patients with MCL, there is still a need for more effective therapies to further enhance survival rates and quality of life.

Recent research has shown promising results with the use of combination treatments for MCL. By combining different types of therapies, such as chemotherapy, immunotherapy, and targeted therapy, researchers believe they may be able to achieve better outcomes for patients with MCL.

One study published in the Journal of Clinical Oncology found that combining the targeted therapy drug ibrutinib with standard chemotherapy significantly improved progression-free survival in patients with newly diagnosed MCL. The study showed that patients who received the combination treatment had a median progression-free survival of 20.8 months, compared to 14.1 months for those who received chemotherapy alone.

Another study published in Blood Advances explored the use of chimeric antigen receptor (CAR) T-cell therapy in combination with chemotherapy for patients with relapsed or refractory MCL. The study found that the combination treatment resulted in high response rates and durable remissions in patients who had previously failed other treatments.

These findings suggest that combination treatments may represent a new standard-of-care for MCL, offering patients improved outcomes and potentially extending their survival. By targeting multiple pathways involved in the development and progression of MCL, combination therapies have the potential to overcome resistance to single-agent treatments and improve overall response rates.

While more research is needed to fully understand the benefits and potential side effects of combination treatments for MCL, these early studies are a promising step towards improving outcomes for patients with this challenging disease. As researchers continue to explore new treatment strategies, the hope is that a new standard-of-care for MCL will soon be established, offering patients better chances of long-term remission and improved quality of life.