# Evaluating the Value of FDA Pre-Submission Meetings: Are They Worth the Time? The U.S. Food and Drug Administration (FDA)...

**The Role of Technology in Enhancing Personalized Brain Health and Improving Outcomes: Insights from Mark Lehmkuhle, PhD, CEO and Founder...

# Common Materials and Devices in Medical Device Manufacturing Medical device manufacturing is a highly specialized field that requires stringent...

**HeartFlow Launches Advanced Interactive Plaque Analysis Platform for Evaluating Patient Risk in Suspected Coronary Artery Disease** *Medical Device News Magazine*...

# A Look Inside Canary Wharf’s Advanced Infectious Disease Testing Facility In the heart of London’s bustling financial district, Canary...

**Bon Secours Mercy Health and Philips Announce Long-Term Strategic Partnership** In a significant move poised to reshape the landscape of...

**Bon Secours Mercy Health and Philips Announce Multi-Year Strategic Partnership** *Medical Device News Magazine* In a significant move poised to...

**Novocuff Secures $26 Million in Oversubscribed Series A Funding to Enhance Preterm Birth Prevention Technology** *Medical Device News Magazine* In...

# 9 Innovative Applications of AI in Medical Device Development Artificial Intelligence (AI) is revolutionizing various sectors, and the field...

**Ideal Medical Solutions Honored at 2024 Medical Device Network Excellence Awards** In a remarkable celebration of innovation and excellence in...

**Government Initiates Program to Enhance Local Production of 113 Cost-Effective Medical Devices, Aiming to Reduce Import Reliance** In a significant...

**Digestiva Secures $18.4 Million in Series A Funding – Reported by Medical Device News Magazine** In a significant development within...

**Mabwell Gains NMPA Approval for Clinical Trial of Innovative Nectin-4 Targeting ADC in Triple-Negative Breast Cancer** In a significant stride...

**Immediate Medicare Coverage Announced for Designated Medical Breakthrough Devices by Knobbe Medical** In a landmark decision poised to revolutionize the...

**WHO Introduces MeDevIS: A Cutting-Edge Platform for Worldwide Medical Device Information** In a significant stride towards enhancing global healthcare, the...

# Comprehensive EDA Guidelines on Recall Classification Rules | RegDesk In the realm of medical devices and pharmaceuticals, ensuring product...

# Guidelines on Recall Classification Rules by the EDA ## Introduction The European Medicines Agency (EMA) and the U.S. Food...

# Comprehensive EDA Guidelines for Initiating Product Recalls | RegDesk In the fast-paced world of product manufacturing and distribution, ensuring...

# Exploring the Limits of Our Molecular Understanding In the vast and intricate world of biology, the molecular level serves...

**Applications of Precision Medicine in Healthcare** Precision medicine, also known as personalized medicine, is revolutionizing the healthcare landscape by tailoring...

# Comprehensive Guide to Breathing Apparatus Manufacturing ## Introduction Breathing apparatuses are critical safety devices designed to provide respiratory protection...

**The Future of Continuous Glucose Monitors: Analyzing Global Expansion and US Market Dominance** Continuous Glucose Monitors (CGMs) have revolutionized diabetes...

**The Future of Continuous Glucose Monitors: Global Expansion and Dominance in the US Market** Continuous Glucose Monitors (CGMs) have revolutionized...

**Global Expansion and US Dominance in the Future of Continuous Glucose Monitors** Continuous Glucose Monitors (CGMs) have revolutionized diabetes management,...

# Guideline for On-Site Inspections Under China’s Good Supply Practice (GSP) Issued ## Introduction China’s pharmaceutical industry has been undergoing...

# Guidelines for On-Site Inspections Under China’s Good Supply Practice (GSP) Issued ## Introduction China’s pharmaceutical industry has seen rapid...

**China’s New Generalized System of Preferences to Take Effect on July 1, 2024** In a significant move aimed at bolstering...

**Implementation of China’s New Generalized System of Preferences (GSP) Set for July 1, 2024** China is set to implement a...

**Implementation of China’s New Generalized System of Preferences (GSP) Starting July 1, 2024** China is set to implement a new...

**Implementation of China’s New Generalized System of Preferences (GSP) Effective July 1, 2024** On July 1, 2024, China will implement...

Genesis MedTech Receives FDA Breakthrough Device Designation for the J-Valve™ Transfemoral System, as Announced on BioSpace

Genesis MedTech, a leading medical technology company, has recently received the prestigious FDA Breakthrough Device Designation for its innovative J-Valve™ Transfemoral System. This breakthrough designation is a significant milestone for the company and highlights the potential of this groundbreaking technology in revolutionizing the treatment of patients with severe aortic regurgitation.

Aortic regurgitation is a condition characterized by the leakage of blood from the aorta back into the left ventricle of the heart. This can lead to various complications, including heart failure, arrhythmias, and even death. Traditionally, open-heart surgery has been the standard treatment for severe cases of aortic regurgitation. However, this procedure is invasive and carries a high risk of complications, especially in elderly or high-risk patients.

The J-Valve™ Transfemoral System offers a minimally invasive alternative to open-heart surgery. It is a transcatheter-based device that can be implanted through a small incision in the patient’s leg, eliminating the need for open-heart surgery. This innovative system consists of a bioprosthetic valve mounted on a self-expanding nitinol frame, which allows for precise positioning and secure anchoring within the native valve.

The FDA Breakthrough Device Designation is granted to medical devices that have the potential to provide more effective treatment or diagnosis of life-threatening or irreversibly debilitating diseases. This designation is intended to expedite the development and review process of such devices, ensuring that patients have timely access to innovative treatments.

Genesis MedTech’s J-Valve™ Transfemoral System has demonstrated promising results in clinical trials, showing significant improvements in patients’ quality of life and reducing the risk of complications associated with traditional open-heart surgery. The breakthrough designation from the FDA acknowledges the potential of this technology to address an unmet medical need and improve patient outcomes.

With this designation, Genesis MedTech will receive enhanced support from the FDA throughout the development and review process. This includes priority review, interactive communication, and access to senior FDA staff, which will help expedite the approval process and bring this innovative technology to patients sooner.

The J-Valve™ Transfemoral System has the potential to revolutionize the treatment of severe aortic regurgitation by offering a less invasive and safer alternative to open-heart surgery. By eliminating the need for sternotomy and cardiopulmonary bypass, this system can significantly reduce the risk of complications and shorten recovery time for patients.

In addition to its potential benefits for patients, the J-Valve™ Transfemoral System also has economic implications. Minimally invasive procedures are generally associated with lower healthcare costs compared to open-heart surgery. By reducing hospital stays, post-operative care, and rehabilitation, this innovative system can help alleviate the financial burden on healthcare systems and improve cost-effectiveness.

Genesis MedTech’s receipt of the FDA Breakthrough Device Designation for the J-Valve™ Transfemoral System is a significant achievement that highlights the potential of this groundbreaking technology in transforming the treatment of severe aortic regurgitation. With expedited development and review processes, patients can look forward to having access to this innovative treatment option sooner, improving their quality of life and reducing the risk of complications associated with traditional open-heart surgery.