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Does Vestibular System Effected in Chronic Obstructive Pulmonary Disease Patients

Studies

Study First Submitted Date 2020-02-06
Study First Posted Date 2020-02-21
Last Update Posted Date 2022-12-02
Start Month Year February 25, 2024
Primary Completion Month Year May 15, 2024
Verification Month Year December 2022
Verification Date 2022-12-31
Last Update Posted Date 2022-12-02

Detailed Descriptions

Sequence: 20800610
Description Chronic Obstructive Pulmonary Disorder (COPD) is a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Hypoxia caused by restrictive airflow is one of the symptoms of COPD. Hypoxia can affect the inner ear and vestibular nuclei. Also, balance impairment can be caused by hypoxia. Previous studies show that balance affected negatively in COPD patients. The aim of this study is to investigate of vestibular system influence in individuals with COPD. A total of 10 COPD patients and 10 healthy adults will include the study. This research is planned to be carried out as a cross-sectional/descriptive research. It’s planned as a pilot study. Respiratory functions (respiratory function test), vestibular functions (head shake test, head trust test, unterberger test) and postural stability (sensory organization test) of participants will be assessed.Comparisons between study and control groups will be made with independent samples t-test for parametric values and Mann Whitney U for non-parametric values.

Conditions

Sequence: 52372678
Name Vestibular Disorder
Downcase Name vestibular disorder

Id Information

Sequence: 40302590
Id Source org_study_id
Id Value 061

Design Groups

Sequence: 55817478 Sequence: 55817479
Title COPD Group Title Control Group
Description Patients who are over 40 years old, diagnosed with COPD Description Healthy adults over 40 years old

Interventions

Sequence: 52683319 Sequence: 52683320 Sequence: 52683321
Intervention Type Other Intervention Type Other Intervention Type Other
Name Respiratory Assessment Name Vestibular Assessment Name Balance Assessment
Description Spirometric measurement Description Assessment of peripheral vestibular dysfunction, angular vestibule ocular reflex, vestibular dysfunction Description Postural stability

Keywords

Sequence: 80144614 Sequence: 80144615 Sequence: 80144616
Name vestibular dysfunction Name COPD Name balance
Downcase Name vestibular dysfunction Downcase Name copd Downcase Name balance

Design Outcomes

Sequence: 178124176 Sequence: 178124177 Sequence: 178124178 Sequence: 178124179 Sequence: 178124180 Sequence: 178124181 Sequence: 178124182 Sequence: 178124183 Sequence: 178124184 Sequence: 178124185
Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary Outcome Type primary
Measure Vestibular Assessment 1 Measure Balance Assessment Measure Respiratory Assessment – Spirometry – Forced expiratory volume in 1 s (FEV1) Measure Respiratory Assessment – Spirometry – Forced vital capacity (FVC) Measure Respiratory Assessment – Spirometry – Vital capacity (VC) Measure Respiratory Assessment – Spirometry – Peak expiratory flow (PEF) Measure Respiratory Assessment – Spirometry – Forced expiratory flow (FEF) Measure Respiratory Assessment – Spirometry – •Inspiratory vital capacity (IVC) Measure Vestibular Assessment 2 Measure Vestibular Assessment 3
Time Frame After the individuals permission, in first 4 minutes Time Frame After the individuals permission, in first 20 minutes Time Frame After the individuals permission, in first 22 minutes Time Frame After the individuals permission, in first 22 minutes Time Frame After the individuals permission, in first 22 minutes Time Frame After the individuals permission, in first 22 minutes Time Frame After the individuals permission, in first 22 minutes Time Frame After the individuals permission, in first 22 minutes Time Frame After the individuals permission, in first 8 minutes Time Frame After the individuals permission, in first 10 minutes
Description Head Shake Test:The head shake test is performed by shaking the head of the patient. The head is rotated at a comfortable range at a frequency of about 2 to 3 Hertz for 10- to 15 seconds. After shaking, the head remains in the center and the eyes of the patient are observed for nystagmus. The head shake test is used to look for signs of dynamic imbalance of vestibular function by evaluating the post-shaking nystagmus. Description Subjects stands on dual force plates and and their anterior posterior sway recorded in different test conditions. Eyes open- stable support Eyes closed- stable support Eyes open- stable support Eyes open-Foam surface Eyes closed-Foam surface Eyes open-Foam surface Description *We will supply the information of test results from patients’ folders.* Forced expiratory volume in 1 s (FEV1) Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive. Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration. Description *We will supply the information of test results from patients’ folders.* FVC, the maximum amount of air that can be exhaled when blowing out as fast as possible Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive. Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration. Description *We will supply the information of test results from patients’ folders.* Vital capacity (VC), the maximum amount of air that can be exhaled when blowing out as fast as possible Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive. Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration. Description *We will supply the information of test results from patients’ folders.* Peak expiratory flow (PEF), the maximal flow that can be exhaled when blowing out at a steady rate Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive. Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration. Description *We will supply the information of test results from patients’ folders.* Forced expiratory flow, also known as mid-expiratory flow; the rates at 25%, 50% and 75% FVC are given Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive. Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration. Description *We will supply the information of test results from patients’ folders.* Inspiratory vital capacity (IVC), the maximum amount of air that can be inhaled after a full expiration Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive. Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration. Description Head Trust Test: A brief, high-acceleration head thrust can test vestibular function of all semicircular canals. Depending on the semicircular canal tested, the head is rotated in a different direction. A corrective catch-up saccade is made in case of vestibular hypofunction. Description Unterberger test: Subjects will close their eyes and begin stepping in place for 60 seconds with shoulder at 90 degrees flexion, arms extended forward. The distance will be measured from the start point to end point.

Browse Conditions

Sequence: 194253395 Sequence: 194253396 Sequence: 194253397 Sequence: 194253398 Sequence: 194253399 Sequence: 194253400 Sequence: 194253401 Sequence: 194253402 Sequence: 194253403 Sequence: 194253404 Sequence: 194253405
Mesh Term Lung Diseases, Obstructive Mesh Term Pulmonary Disease, Chronic Obstructive Mesh Term Vestibular Diseases Mesh Term Lung Diseases Mesh Term Respiratory Tract Diseases Mesh Term Chronic Disease Mesh Term Disease Attributes Mesh Term Pathologic Processes Mesh Term Labyrinth Diseases Mesh Term Ear Diseases Mesh Term Otorhinolaryngologic Diseases
Downcase Mesh Term lung diseases, obstructive Downcase Mesh Term pulmonary disease, chronic obstructive Downcase Mesh Term vestibular diseases Downcase Mesh Term lung diseases Downcase Mesh Term respiratory tract diseases Downcase Mesh Term chronic disease Downcase Mesh Term disease attributes Downcase Mesh Term pathologic processes Downcase Mesh Term labyrinth diseases Downcase Mesh Term ear diseases Downcase Mesh Term otorhinolaryngologic diseases
Mesh Type mesh-list Mesh Type mesh-list Mesh Type mesh-list Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor

Sponsors

Sequence: 48507421
Agency Class OTHER
Lead Or Collaborator lead
Name Nimet Sermenli Aydın

Central Contacts

Sequence: 12059980 Sequence: 12059981
Contact Type primary Contact Type backup
Name Nimet Sermenli Aydın, MSc Name Halit Selçuk, Msc
Phone +905079955111 Phone +905384855543
Email nimetsermenli@gmail.com Email selcukhalit@gmail.com
Role Contact Role Contact

Design Group Interventions

Sequence: 68423631 Sequence: 68423632 Sequence: 68423633 Sequence: 68423634 Sequence: 68423635 Sequence: 68423636
Design Group Id 55817478 Design Group Id 55817479 Design Group Id 55817478 Design Group Id 55817479 Design Group Id 55817478 Design Group Id 55817479
Intervention Id 52683319 Intervention Id 52683319 Intervention Id 52683320 Intervention Id 52683320 Intervention Id 52683321 Intervention Id 52683321

Eligibilities

Sequence: 30881910
Sampling Method Non-Probability Sample
Gender All
Minimum Age 40 Years
Maximum Age 65 Years
Healthy Volunteers Accepts Healthy Volunteers
Population The study group will be selected from Respiratory Disease Hospital – (Süreyyapaşa Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi) The control group will be invited from the community by announcements.
Criteria For study group Inclusion Criteria: Volunteering to participate in the study Diagnosed with COPD Exclusion Criteria: Communication – Coordination problems of patients Using medicine which is increasing the risk of fall Any neurologic or musculoskeletal disorders which affect mobility and balance Loss of hearing For control group Inclusion Criteria: Volunteering to participate in the study Exclusion Criteria: Communication – Coordination problems of patients Using medicine which is increasing the risk of fall Any neurologic, musculoskeletal or respiratory disorders which affect mobility and balance Loss of hearing
Adult True
Child False
Older Adult True

Calculated Values

Sequence: 254103694
Registered In Calendar Year 2020
Were Results Reported False
Has Single Facility False
Minimum Age Num 40
Maximum Age Num 65
Minimum Age Unit Years
Maximum Age Unit Years
Number Of Primary Outcomes To Measure 10

Designs

Sequence: 30627682
Observational Model Case-Control
Time Perspective Cross-Sectional

Intervention Other Names

Sequence: 26773340 Sequence: 26773341 Sequence: 26773342 Sequence: 26773343 Sequence: 26773344
Intervention Id 52683319 Intervention Id 52683320 Intervention Id 52683320 Intervention Id 52683320 Intervention Id 52683321
Name Respiratory Function Test Name Head shake test Name Head trust test Name Unterberger test Name Sensory organization test

Responsible Parties

Sequence: 28994250
Responsible Party Type Sponsor-Investigator
Name Nimet Sermenli Aydın
Title Reseach Assisstant
Affiliation Trakya University