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Predictors of Chronic Kidney Disease Among Type 2 Diabetic Patients in Assiut University Hospitals

Studies

Study First Submitted Date 2023-04-27
Study First Posted Date 2023-05-06
Last Update Posted Date 2023-05-06
Start Month Year March 1, 2024
Primary Completion Month Year March 28, 2024
Verification Month Year April 2023
Verification Date 2023-04-30
Last Update Posted Date 2023-05-06

Detailed Descriptions

Sequence: 20583354
Description Globally, the total number of people with diabetes is estimated to increase from 415 million (8.8%) in 2015 to 642 million (10.4%) in 2040, with the largest alterations expected to occur in the urban population of low- to middle-income countries (LMICs)1. Of them, type 2 diabetes mellitus (T2DM) accounts for more than 90% of people with diabetes2,3. By 2040, the difference worldwide is projected to broaden, with 477.9 million affected people living in urban areas and 163.9 million in rural areas1. It has been postulated that the burden of diabetes and its complications in the LMICs may be contributed by the economic development and rapid urbanisation via increased caloric intake and the adoption of a sedentary lifestyle2,4,5. More importantly, the most striking demo graphic change to diabetes prevalence in global terms also seems to be related to the growth of the proportion of the elderly population6. Despite rates of diabetes-related complications such as CVDs decreasing significantly in the past two decades, it has not translated nearly as well as kidney complications7. Approximately 10% of deaths in people with T2DM are attributable to kidney failure8. It is well-established that diabetes-related chronic kidney disease (CKD) is the leading cause of end-stage kidney disease (ESKD) in T2DM patients worldwide9,10. In our study, we aim to identify and classify patients attending diabetic outpatient clinic with both CKD and

Facilities

Sequence: 198702349
Status Recruiting
Name Assiut
City Assiut
Zip 088
Country Egypt

Facility Contacts

Sequence: 27951588 Sequence: 27951589
Facility Id 198702349 Facility Id 198702349
Contact Type primary Contact Type backup
Name Muhammed Al Abualsaud, Master Name Peter At Munir
Email Aboalsaud25@gmail.com
Phone ‪+20 106 923 9438‬ Phone 01553529181

Conditions

Sequence: 51814677
Name Type 2 Diabetes With Renal Manifestations
Downcase Name type 2 diabetes with renal manifestations

Id Information

Sequence: 39874771
Id Source org_study_id
Id Value ckd in tybe 2 dm

Countries

Sequence: 42273349
Name Egypt
Removed False

Design Groups

Sequence: 55236373 Sequence: 55236374
Title CKD patients with T2DM on regular HD Title CKD patients with T2DM not on regular HD
Description CKD patients with T2DM attending Assuit university diabetic outpatients clinic and ESRD on regular HD at dialysis unit of Assuit University Hospital Description CKD patients with T2DM attending Assuit university diabetic outpatients clinic and ESRD not on regular HD at dialysis unit of Assuit University Hospital

Design Outcomes

Sequence: 176225507 Sequence: 176225508
Outcome Type primary Outcome Type secondary
Measure predictors of CKD among T2DM patients attending Assiut University Hospitals. To classify our patients into stages according to KDIGO guidelines Measure the possible risk factors contributing to progessing CKD in T2DM patients.
Time Frame 3 years Time Frame 3 years
Description To identify predictors of CKD among T2DM patients attending Assiut University Hospitals. To classify our patients into stages according to KDIGO guidelines Description To identify the possible risk factors contributing to progessing CKD in T2DM patients.

Browse Conditions

Sequence: 192051311 Sequence: 192051312 Sequence: 192051313 Sequence: 192051314 Sequence: 192051315 Sequence: 192051316 Sequence: 192051317 Sequence: 192051318 Sequence: 192051319 Sequence: 192051320 Sequence: 192051321 Sequence: 192051322 Sequence: 192051323 Sequence: 192051324 Sequence: 192051325
Mesh Term Kidney Diseases Mesh Term Renal Insufficiency, Chronic Mesh Term Diabetic Nephropathies Mesh Term Urologic Diseases Mesh Term Female Urogenital Diseases Mesh Term Female Urogenital Diseases and Pregnancy Complications Mesh Term Urogenital Diseases Mesh Term Male Urogenital Diseases Mesh Term Renal Insufficiency Mesh Term Chronic Disease Mesh Term Disease Attributes Mesh Term Pathologic Processes Mesh Term Diabetes Complications Mesh Term Diabetes Mellitus Mesh Term Endocrine System Diseases
Downcase Mesh Term kidney diseases Downcase Mesh Term renal insufficiency, chronic Downcase Mesh Term diabetic nephropathies Downcase Mesh Term urologic diseases Downcase Mesh Term female urogenital diseases Downcase Mesh Term female urogenital diseases and pregnancy complications Downcase Mesh Term urogenital diseases Downcase Mesh Term male urogenital diseases Downcase Mesh Term renal insufficiency Downcase Mesh Term chronic disease Downcase Mesh Term disease attributes Downcase Mesh Term pathologic processes Downcase Mesh Term diabetes complications Downcase Mesh Term diabetes mellitus Downcase Mesh Term endocrine system diseases
Mesh Type mesh-list Mesh Type mesh-list Mesh Type mesh-list Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor Mesh Type mesh-ancestor

Sponsors

Sequence: 47987332
Agency Class OTHER
Lead Or Collaborator lead
Name Assiut University

Overall Officials

Sequence: 29075913
Role Principal Investigator
Name Muhammed Al Abualsaud
Affiliation Assiut University

Central Contacts

Sequence: 11936242 Sequence: 11936243
Contact Type primary Contact Type backup
Name Muhammed Al Abualsaud Name Peter At Munir
Phone ‪+20 106 923 9438‬ Phone 01553529181
Email Aboalsaud25@gmail.com
Role Contact Role Contact

Eligibilities

Sequence: 30556263
Sampling Method Probability Sample
Gender All
Minimum Age 18 Years
Maximum Age N/A
Healthy Volunteers No
Population All type 2 diabetic &ckd patient older than 18 years
Criteria Inclusion Criteria: – Patients with T2DM aged 18 years or older. For patients whom eGFR values < or =60 ml/min/1.73m2. Patient with type 2 DM and ESRD on regular HD with duration less than 1 year Exclusion Criteria: Having kidney transplantation incomplete data on glycemic control. Patients with type 2 DM and ESRD on regular HD with duration more than 1 year. Pregnant woman. Patients with advanced comorbides(cardiac, hepatic,
Adult True
Child False
Older Adult True

Calculated Values

Sequence: 254238961
Number Of Facilities 1
Registered In Calendar Year 2023
Were Results Reported False
Has Us Facility False
Has Single Facility True
Minimum Age Num 18
Minimum Age Unit Years
Number Of Primary Outcomes To Measure 1
Number Of Secondary Outcomes To Measure 1

Designs

Sequence: 30304592
Observational Model Cohort
Time Perspective Cross-Sectional

Responsible Parties

Sequence: 28683180
Responsible Party Type Principal Investigator
Name Muhammed Ali Aboalsaud
Title Aboalsaud
Affiliation Assiut University