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Can Sugar Patterns Help To Predict Kidney Disease? –

The solution to look at sugar patterns

Proteins like IgA can be changed when sugars are attached to them. When someone has kidney disease, the patterns of sugars on proteins can change and these changes can alter the shape and job of the protein, which can affect kidney health.

Andrew will analyse how these changes in sugar patterns might contribute to IgA-GN, and whether they might be able to explain why kidney disease can affect adults and children differently. He will also study how the sugar patterns change over time to find potential markers that show how the disease might progress or get better. 

Andrew will develop methods to pick up changes in these sugar patterns using devices that can be used at home and posted to the lab, making it easier for more people to participate.