Ogunnigbo, O. et al. Exploring the antimicrobial stewardship educational needs of healthcare students and the potential of an antimicrobial prescribing app as an educational tool in selected African countries. Antibiotics 11(5), 691 (2022).
Baddley, J. W., Stroud, T. P., Salzman, D. & Pappas, P. G. Invasive mold infections in allogeneic bone marrow transplant recipients. Clin. Infect. Dis. 32, 1319–1324 (2001).
Roemer, T. & Krysan, D. J. Antifungal drug development: challenges, unmet clinical needs, and new approaches. Cold Spring Harb. Perspect. Med. 4, a019703–a019703 (2014).
Pappas, P. G. et al. A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients. Clin. Infect. Dis. 37, 634–643 (2003).
Sardi, J. C. O., Scorzoni, L., Bernardi, T., Fusco-Almeida, A. M. & Mendes Giannini, M. J. S. Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options. J. Med. Microbiol. 62, 10–24 (2013).
Seneviratne, C. J. & Rosa, E. A. R. Editorial: Antifungal drug discovery: New theories and new therapies. Front. Microbiol. 7, 728 (2016).
Perfect, J. R. The antifungal pipeline: A reality check. Nat. Rev. Drug Discov. 16, 603–616 (2017).
Kachroo, A. H. et al. Systematic humanization of yeast genes reveals conserved functions and genetic modularity. Science 1979(348), 921–925 (2015).
Chatterjee, S., Ghosh, R. & Mandal, N. C. Inhibition of biofilm- and hyphal- development, two virulent features of Candida albicans by secondary metabolites of an endophytic fungus Alternaria tenuissima having broad spectrum antifungal potential. Microbiol. Res. 232, 126386 (2020).
Fanning, S. & Mitchell, A. P. Fungal biofilms. PLoS Pathog. 8, e1002585 (2012).
Cragg, G. M. & Newman, D. J. Natural products: A continuing source of novel drug leads. Biochim. Biophys. Acta Gen. Subj. 1830, 3670–3695 (2013).
Arora, P., Ahmad, T., Farooq, S. & Riyaz-Ul-Hassan, S. Endophytes: A hidden treasure of novel antimicrobial metabolites. In Antibacterial Drug Discovery to Combat MDR 165–192 (Springer Singapore, 2019). https://doi.org/10.1007/978-981-13-9871-1_8.
Schulz, B., Wanke, U., Draeger, S. & Aust, H.-J. Endophytes from herbaceous plants and shrubs: effectiveness of surface sterilization methods. Mycol. Res. 97, 1447–1450 (1993).
Santra, H. K. & Banerjee, D. Production, optimization, characterization and drought stress resistance by β-glucan-rich heteropolysaccharide from an endophytic fungi Colletotrichum alatae LCS1 isolated from clubmoss (Lycopodium clavatum). Front. Fungal Biol. 2, 796010 (2022).
Santra, H. K., Maity, S. & Banerjee, D. Production of bioactive compounds with broad spectrum bactericidal action, bio-film inhibition and antilarval potential by the secondary metabolites of the endophytic fungus Cochliobolus sp. APS1 isolated from the Indian medicinal herb Andrographis paniculata. Molecules 27, 1459 (2022).
Rai, N. et al. Ethyl acetate extract of Colletotrichum gloeosporioides promotes cytotoxicity and apoptosis in human breast cancer cells. ACS Omega 8, 3768–3784 (2023).
Santra, H. K. & Banerjee, D. Production, optimisation and evaluation of plant growth promoting abilities of heteropolysaccharides isolated from endophytic fungi Mucor sp. HELF2. Front. Microbiol. 13, 5449 (2022).
Dal’Rio, I., Mateus, J. R. & Seldin, L. Unraveling the Tropaeolum majus L. (Nasturtium) root-associated bacterial community in search of potential biofertilizers. Microorganisms 10, 638 (2022).
Gasparotto Junior, A. et al. Antihypertensive effects of isoquercitrin and extracts from Tropaeolum majus L.: Evidence for the inhibition of angiotensin converting enzyme. J. Ethnopharmacol. 134, 363–372 (2011).
Jakubczyk, K., Janda, K., Watychowicz, K., Lukasiak, J. & Wolska, J. Garden nasturtium (Tropaeolum majus L.)-a source of mineral elements and bioactive compounds. Roczniki Państwowego Zakładu Higieny 69(2), 119 (2018).
Pena, L. C. et al. Muscodor brasiliensis sp. Nov. produces volatile organic compounds with activity against Penicillium digitatum. Microbiol. Res. 221, 28–35 (2019).
Baiome, B. A. et al. Identification of volatile organic compounds produced by Xenorhabdus indica strain AB and investigation of their antifungal activities. Appl. Environ. Microbiol. 88(13), e00155-e222 (2022).
Chatterjee, S., Kuang, Y., Splivallo, R., Chatterjee, P. & Karlovsky, P. Interactions among filamentous fungi Aspergillus niger, Fusarium verticillioides and Clonostachys rosea: fungal biomass, diversity of secreted metabolites and fumonisin production. BMC Microbiol. 16, 83–83. https://doi.org/10.1186/s12866-016-0698-3 (2016).
Li, J., Fei, Gu., Runian, Wu., Yang, JinKui & Zhang, K.-Q. Phylogenomic evolutionary surveys of subtilase superfamily genes in fungi. Sci. Rep. 7(1), 1–15 (2017).
Peng, Y. et al. Research progress on phytopathogenic fungi and their role as biocontrol agents. Front. Microbiol. 12, 1209 (2021).
Sugden, R., Kelly, R. & Davies, S. Combatting antimicrobial resistance globally. Nat. Microbiol. 1, 16187 (2016).
Santra, H. K. & Banerjee, D. Bioactivity study and metabolic profiling of Colletotrichum alatae LCS1, an endophyte of club moss Lycopodium clavatum L. PLoS ONE 17, e0267302 (2022).
Biswas, K., Bhattarcharya, D., Saha, M., Mukherjee, J. & Karmakar, S. Evaluation of antimicrobial activity of the extract of Streptomyces euryhalinus isolated from the Indian Sundarbans. Arch Microbiol 204, 34 (2022).
Kupferwasser, L. I. et al. Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus. J. Clin. Investig. 112, 222–233 (2003).
Schaller, M. et al. Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis. Mol. Microbiol. 34, 169–180 (1999).
Borg, M. & Rüchel, R. Expression of extracellular acid proteinase by proteolytic Candida spp. during experimental infection of oral mucosa. Infect. Immun. 56, 626–631 (1988).
Chatterjee, S., Ghosh, S. & Mandal, N. C. Potential of an endophytic fungus Alternaria tenuissima PE2 isolated from Psidium guajava L. for the production of bioactive compounds. South Afr. J. Bot. 150, 658–670 (2022).
Santra, H. K. & Banerjee, D. Broad-spectrum antimicrobial action of cell-free culture extracts and volatile organic compounds produced by endophytic fungi Curvularia eragrostidis. Front. Microbiol. 13, 0561 (2022).
Chatterjee, S., Ghosh, R. & Mandal, N. C. Production of bioactive compounds with bactericidal and antioxidant potential by endophytic fungus Alternaria alternata AE1 isolated from Azadirachta indica A. Juss. PLoS ONE 14, e0214744. https://doi.org/10.1371/journal.pone.0214744 (2019).
Cavalheiro, M. & Teixeira, M. C. Candida biofilms: Threats, challenges, and promising strategies. Front. Med. 5, 28 (2018).
Chowdhury, S., Ghosh, S. & Gond, S. K. Anti-MRSA and clot lysis activities of Pestalotiopsis microspora isolated from Dillenia pentagyna Roxb. J. Basic Microbiol. 63, 340–358 (2022).
Khan, M. S., Ahmad, I. & Cameotra, S. Phenyl aldehyde and propanoids exert multiple sites of action towards cell membrane and cell wall targeting ergosterol in Candida albicans. AMB Express 3, 54 (2013).
Ghannoum, M. A. & Rice, L. B. Antifungal agents: Mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 12, 501–517 (1999).
Zhou, Y. et al. ERG3 and ERG11 genes are critical for the pathogenesis of Candida albicans during the oral mucosal infection. Int. J. Oral Sci. 10, 9 (2018).
Bashir, A. et al. A secondary metabolite of Cercospora sp., associated with Rosa damascena Mill., inhibits proliferation, biofilm production, ergosterol synthesis and other virulence factors in Candida albicans. Microb. Ecol. 85, 1276–1287. https://doi.org/10.1007/s00248-022-02003-x (2022).
Holmes, G. J. & Clark, C. A. First report of Geotrichum candidum as a pathogen of sweetpotato storage roots from flooded fields in North Carolina and Louisiana. Plant Dis. 86, 695–695 (2002).
Williamson, B., Tudzynski, B., Tudzynski, P. & van Kan, J. A. L. Botrytis cinerea: the cause of grey mould disease. Mol. Plant Pathol. 8, 561–580 (2007).
Verma, R. Biology and control of Rhizoctonia solani on rapeseed: A review. Phytoprotection 77, 99–111 (1996).
Agrios, G. N. Plant Pathology (Elsevier Academic Press, 2005).
Michielse, C. B. & Rep, M. Pathogen profile update: Fusarium oxysporum. Mol. Plant Pathol. 10, 311–324 (2009).
Meena, M., Gupta, S. K., Swapnil, Z. & A., Dubey, M. K., and Upadhyay, R. S.,. Alternaria toxins: Potential virulence factors and genes related to pathogenesis. Front. Microbiol. 8, 1451. https://doi.org/10.3389/fmicb.2017.01451 (2017).
Dagenais, T. R. T. & Keller, N. P. Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clin. Microbiol. Rev. 22, 447–465 (2009).
Banerjee, D. et al. Muscodor albus strain GBA, an endophytic fungus of Ginkgo biloba from United States of America, produces volatile antimicrobials. Mycology 1, 179–186 (2010).
Banerjee, D., Pandey, A., Jana, M. & Strobel, G. Muscodor albus MOW12 an endophyte of Piper nigrum L. (Piperaceae) collected from North East India produces volatile antimicrobials. Indian J. Microbiol. 54, 27–32 (2014).
Singh, S. K. et al. An endophytic Phomopsis sp. possessing bioactivity and fuel potential with its volatile organic compounds. Microb. Ecol. 61, 729–739 (2011).
Strobel, G. et al. An endophytic/pathogenic Phoma sp. from creosote bush producing biologically active volatile compounds having fuel potential. FEMS Microbiol. Lett. 320, 87–94 (2011).
Saxena, S. & Strobel, G. A. Marvellous Muscodor spp.: Update on their biology and applications. Microb. Ecol. 82, 5–20 (2021).
Yeh, C. C., Wang, C. J., Chen, Y. J., Tsai, S. H. & Chung, W. H. Potential of a volatile-producing endophytic fungus Nodulisporium sp. PDL-005 for the control of Penicillium digitatum. Biol. Control 152, 1044 (2021).
Oonmetta-Aree, J., Suzuki, T., Gasaluck, P. & Eumkeb, G. Antimicrobial properties and action of galangal (Alpinia galanga Linn.) on Staphylococcus aureus. LWT Food Sci. Technol. 39, 1214–1220. https://doi.org/10.1016/j.lwt.2005.06.015 (2006).
Bruce, A., Stewart, D., Verrall, S. & Wheatley, R. E. Effect of volatiles from bacteria and yeast on the growth and pigmentation of sapstain fungi. Int. Biodeterior Biodegrad. 51, 101–108. https://doi.org/10.1016/S0964-8305(02)00088-4 (2003).
Ye, X. et al. Biocidal effects of volatile organic compounds produced by the myxobacterium Corrallococcus sp. EGB against fungal phytopathogens. Food Microbiol. 91, 103502. https://doi.org/10.1016/j.fm.2020.103502 (2020).
Bassam, S. E., Benhamou, N. & Carisse, O. The role of melanin in the antagonistic interaction between the apple scab pathogen Venturia inaequalis and Microsphaeropsis ochracea. Can J Microbiol 48, 349–358. https://doi.org/10.1139/w02-030 (2002).
Gupta, S., Kaul, S., Singh, B., Vishwakarma, R. A. & Dhar, M. K. Production of gentisyl alcohol from Phoma herbarum endophytic in Curcuma longa L. and its antagonistic activity towards leaf spot pathogen Colletotrichum gloeosporioides. Appl. Biochem. Biotechnol. 180, 1093–1109 (2016).
Gupta, S. et al. Diversity and biological activity of fungal endophytes of Zingiber officinale Rosc. with emphasis on Aspergillus terreus as a biocontrol agent of its leaf spot. Biocatal. Agric. Biotechnol. 39, 102234 (2022).
Sharma, S., Gupta, S., Dhar, M. K. & Kaul, S. Diversity and bioactive potential of culturable fungal endophytes of medicinal shrub Berberis aristata DC.: A first report. Mycobiology 46, 370–381 (2018).
White, T. J., Bruns, T., Lee, S. & Taylor, J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In PCR Protocols: A Guide to Methods and Applications (eds Innis, M. H. et al.) 315–322 (Academic Press, 1990).
Bauer, A. W., Kirby, W. M., Sherris, J. C. & Turck, M. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 45(4), 493–496 (1966).
Burton, K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 62, 315–323 (1956).
Lowry, O. H., Rosenbrough, N. J., Farr, A. L. & Randall, R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 255–275. https://doi.org/10.1016/S0021-9258(19)52451-6 (1951).
Mandal, N. C. & Chakrabartty, P. K. Succinate- mediated catabolic repression of enzymes of glucose metabolism in root- nodule bacteria. Curr. Microbiol. 26, 247–251 (1993).
Ibrahim, H. R., Sugimoto, Y. & Aoki, T. Ovotransferrin antimicrobial peptide (OTAP-92) kills bacteria through a membrane damage mechanism. Biochim. Biophys. Acta 1523, 196–205 (2000).
Carlisle, P. L. & Kadosh, D. Candida albicans Ume6, a filament-specific transcriptional regulator, directs hyphal growth via a pathway involving Hgc1 cyclin-related protein. Eukaryot Cell 9, 1320–1328 (2010).
Sun, L., Liao, K. & Wang, D. Effects of magnolol and honokiol on adhesion, yeast-hyphal transition, and formation of biofilm by Candida albicans. PLoS ONE 10, e0117695 (2015).
Lorian, V. (ed.) Antibiotics in Laboratory Medicine (Lippincott Williams & Wilkins, 2005).
Jadhav, S., Shah, R., Bhave, M. & Palombo, E. A. Inhibitory activity of yarrow essential oil on Listeria planktonic cells and biofilms. Food Control 29, 125–130 (2013).
Orhan, G., Bayram, A., Zer, Y. & Balci, I. Synergy tests by E test and checkerboard methods of antimicrobial combinations against Brucella melitensis. J. Clin. Microbiol. 43, 140–143 (2005).
Prinsloo, A., van Straten, A. M. S. & Weldhagen, G. F. Antibiotic synergy profiles of multidrug-resistant Pseudomonas aeruginosa in a nosocomial environment. South. Afr. J. Epidemiol. Infect. 23, 7–9 (2008).
Kaur, G., Balamurugan, P., Vasudevan, S., Jadav, S. & Princy, S. A. Antimicrobial and antibiofilm potential of acyclic amines and diamines against multi-drug resistant Staphylococcus aureus. Front. Microbiol. 8, 01767 (2017).
Sundararaman, M., Rajesh Kumar, R., Venkatesan, P. & Ilangovan, A. 1-Alkyl-(N, N-dimethylamino)pyridinium bromides: inhibitory effect on virulence factors of Candida albicans and on the growth of bacterial pathogens. J. Med. Microbiol. 62, 241–248 (2013).
da Rocha Neto, A. C., Maraschin, M. & Di Piero, R. M. Antifungal activity of salicylic acid against Penicillium expansum and its possible mechanisms of action. Int. J. Food Microbiol. 215, 64–70. https://doi.org/10.1016/j.ijfoodmicro.2015.08.018 (2015).
Paul, S., Dubey, R., Maheswari, D. & Kang, S. C. Trachyspermum ammi (L.) fruit essential oil influencing on membrane permeability and surface characteristics in inhibiting food-borne pathogens. Food Control 22, 725–731. https://doi.org/10.1016/j.foodcont.2010.11.003 (2011).
Pinkerton, F. & Strobel, G. Serinol as an activator of toxin production in attenuated cultures of Helminthosporium sacchari. Proc. Natl. Acad. Sci. 73, 4007–4011 (1976).
Mitchell, A. M., Strobel, G. A., Moore, E., Robison, R. & Sears, J. Volatile antimicrobials from Muscodor crispans, a novel endophytic fungus. Microbiology 156, 270–277 (2010).
Park, M. S. et al. Potential of the volatile-producing fungus Nodulisporium sp. CF016 for the control of postharvest diseases of apple. Plant Pathol. J. 26(3), 253–259 (2010).
Wang, Y., Yang, M.-H., Wang, X.-B., Li, T.-X. & Kong, L.-Y. Bioactive metabolites from the endophytic fungus Alternaria alternata. Fitoterapia 99, 153–158 (2014).
Tomsheck, A. R. et al. Hypoxylon sp., an endophyte of Persea indica, producing 1,8-cineole and other bioactive volatiles with fuel potential. Microb. Ecol. 60, 903–914 (2010).
Jemimah Naine, S., Subathra Devi, C., Mohanasrinivasan, V. & Vaishnavi, B. Bioactive potential of marine derived strain Streptomyces brasiliensis VITJS9 isolated from South East Coast of Tamil Nadu, India. Natl. Acad. Sci. Lett. 38, 221–224 (2015).
Wu, Y. et al. A new insight into 6-Pentyl-2H-pyran-2-one against Peronophythora litchii via TOR pathway. J. Fungi 9(8), 863 (2023).
Liu, M. et al. Comparative physiological and transcriptome analysis provide insights into the inhibitory effect of 6-pentyl-2H-pyran-2-one on Clarireedia jacksonii. Pestic. Biochem. Physiol. 193, 105456 (2023).
Calvo, H. et al. Antifungal activity of the volatile organic compounds produced by Bacillus velezensis strains against postharvest fungal pathogens. Postharvest Biol. Technol. 166, 111208 (2020).
Yang, X. et al. Two novel phenethylamine alkaloids from Streptomyces sp. YIM10049. Nat. Prod. Commun. 7(12), 1934 (2012).
Balogun, O. S., Ajayi, O. S. & Adeleke, A. J. Hexahydrofarnesyl acetone-rich extractives from Hildegardia barteri. J. Herbs Spices Med. Plants 23(4), 393–400 (2017).
Kumari, S. et al. GC-MS analysis, antioxidant and antifungal studies of different extracts of Chaetomium globosum isolated from Urginea indica. BioMed Res. Int. 2022, 1–12 (2022).
Das, D. et al. Phytochemical constituents, antimicrobial properties and bioactivity of marine red seaweed (Kappaphycus alvarezii) and seagrass (Cymodocea serrulata). Foods 12(14), 2811 (2023).
Wang, Y. Y., Zheng, C. Z., Wang, L. & Xu, L. Synthesis, Crystal Structure and Antibacterial Activity of 4-Hydroxy-Benzaldehyde Benzoyl Hydrazone. Advanced Materials Research 893, 3–6 (2014).
Santra, H. K. & Banerjee, D. Antifungal activity of volatile and non-volatile metabolites of endophytes of Chloranthus elatior Sw. Front. Plant Sci. 14, 1156323 (2023).
Ribeiro, L. S. et al. Volatile compounds for biotechnological applications produced during competitive interactions between yeasts and fungi. J. Basic Microbiol. 63, 658–667 (2023).
Guluma, T., Babu, N., Teju, E. & Dekebo, A. Phytochemical investigation and evaluation of antimicrobial activities of Brucea antidysenterica leaves. Chem. Data Collect. 28, 100433 (2020).
Karrouchi, K. et al. Synthesis and pharmacological activities of pyrazole derivatives: A review. Molecules 23(1), 134 (2018).
Tahri, D. et al. Biosynthesis and biological activities of carvone and carvotanacetone derivatives. Rev. Brasil. Farmacogn. 32(5), 708–723 (2022).
Spencer, P. V. D. et al. Chemical composition, antioxidant and antibacterial activities of essential oil from Cymbopogon densiflorus (Steud.) Stapf flowers. J. Essent. Oil Bearing Plants 24(1), 40–52 (2021).
Polatoğlu, K., Karakoç, Ö. C., Demirci, B. & Başer, K. H. C. Chemical composition and insecticidal activity of edible garland (Chrysanthemum coronarium L.) essential oil against the granary pest Sitophilus granarius L. (Coleoptera). J. Essent. Oil Res. 30(2), 120–130 (2018).
Dalli, M. et al. Molecular composition and antibacterial effect of five essential oils extracted from Nigella sativa L. seeds against multidrug-resistant bacteria: a comparative study. Evid. Based Complement. Altern. Med. 2021(1), 9 (2021).
Szkudlarek, M., Heine, E., Keul, H., Beginn, U. & Möller, M. Synthesis, characterization, and antimicrobial properties of peptides mimicking copolymers of maleic anhydride and 4-methyl-1-pentene. Int. J. Mol. Sci. 19(9), 2617 (2018).
Petrović, J. et al. Individual stereoisomers of verbenol and verbenone express bioactive features. J. Mol. Struct. 1251, 131999 (2022).
Lira, M. H. P. D. et al. Antimicrobial activity of geraniol: An integrative review. J. Essent. Oil Res. 32(3), 187–197 (2020).
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